Influence of Mikania laevigata Extract over the Genotoxicity Induced by Alkylating Agents
نویسندگان
چکیده
منابع مشابه
Influence of Mikania laevigata Extract over the Genotoxicity Induced by Alkylating Agents
Medicinal plants are still widely used worldwide; yet for some species, little or no information is available concerning their biological activity, specially their genotoxic and antimutagenic potential. Mikania laevigata (Asteraceae) is a native plant from South America, and its extracts are largely used to treat respiratory complaints. The aim of the present work was then to evaluate, in vivo,...
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15 صفحه اولObtaining a Dry Extract from the Mikania laevigata Leaves with Potential for Antiulcer Activity
BACKGROUND Mikania laevigata leaves are commonly used in Brazil as a medicinal plant. OBJECTIVE To obtain hydroalcoholic dried extract by nebulization and evaluate its antiulcerogenic potential. MATERIALS AND METHODS Plant material and hydroalcoholic extract were processed and analyzed for their physicochemical characteristics. A method using HPLC was validated to quantify coumarin and o-co...
متن کاملCoumarin content and physicochemical profile of Mikania laevigata extracts.
The 'guaco' lianous herb Mikania laevigata, which is widespread in Southern Brazil, is traditionally used to treat bronchitis, asthma and cough. This work investigates the influence of the extraction method, solvent:drug ratio, ethanol proportion, harvest season (summer or winter) and solvent heating on the physicochemical profile of the extracts (dry weight, density, pH) and the coumarin (1,2-...
متن کاملEffects of a Mikania laevigata extract on bone resorption and RANKL expression during experimental periodontitis in rats
OBJECTIVES The Mikania laevigata extract (MLE) (popularly known in Brazil as "guaco") possesses anti-inflammatory properties. In the present study we tested the effects of MLE in a periodontitis experimental model in rats. We also investigated possible mechanisms underlying such effects. MATERIAL AND METHODS Periodontal disease was induced by a ligature placed around the mandibular first mola...
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ژورنال
عنوان ژورنال: ISRN Toxicology
سال: 2013
ISSN: 2090-6196
DOI: 10.1155/2013/521432